The crosstalk between alternative splicing and circular RNA in cancer: pathogenic insights and therapeutic implications

Abstract RNA splicing is a fundamental step of gene expression.While constitutive splicing removes introns and joins exons unbiasedly, alternative splicing (AS) selectively determines the assembly of exons and introns to generate RNA variants corresponding to the same transcript.The biogenesis of circular RNAs (circRNAs) is inextricably associated

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Explant Methodology for Analyzing Neuroblast Migration

The subventricular zone (SVZ) in the mammalian forebrain contains stem/progenitor cells that migrate through the rostral migratory stream (RMS) to the olfactory bulb throughout adulthood.SVZ-derived explant cultures provide XL Twin Mattress a convenient method to assess factors regulating the intermediary stage of neural stem/progenitor cell migrat

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Analysis of Microtremor Exploration Application and Construction Monitoring in a Large-Diameter Shield Tunnel

In recent years, shield tunneling has shown many advantages with the development of underground rail traffic.Geological exploration plays a significant role in tunnel engineering, and detailed geological exploration results can guide the successful construction of a tunnel.This research relies on a super large-diameter shield tunnel construction, u

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PARTICIPATION OF THE 9TH RIFLE CORPS IN THE KERCH-FEODOSIAN LANDING OPERATION AND THE BATTLES FOR THE EXPANSION OF THE BRIDGEHEAD

With the use of archival documents, the actions of units and formations of the 9th rifle corps of the COENZYME Q10 400 MG 44th army of the Caucasian front during the liberation of Feodosia and in the battles for the expansion of the bridgehead in the South-Eastern Crimea are revealed.In fact, the rifle corps during the operation was disbanded in Cr

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